Tue, 19 Feb 2019
Notice of upcoming webinar
Members of the Ontario Molecular Pathology Research Network (OMPRN) may be interested in the webinar listed below describing a method for developing customized NGS-based tumour panels for potential clinical implementation. This webinar is presented by GenomeWeb. OMPRN is not the organizer of this webinar.
Rapid Testing of Solid Tumour Samples Using a Single-Vial NGS Assay
This webinar will demonstrate how clinical laboratories can develop their own customized, targeted, next-generation sequencing (NGS)-based solid tumour panels.
Clinical labs that offer NGS-based tumour tests with different ranges of genes or mutations need to develop and validate customized assays that are accurate, sensitive, robust, affordable, easy to use and free from cross-sample contamination. Customization, however, can present significant obstacles for labs that lack the experience or financial resources required to design, develop and validate the assay and interpret novel variants.
In this webinar, Dr. Paul Waring, Professor of Pathology at the University of Melbourne, will discuss how clinical labs can overcome these challenges. The webinar will provide details of Pillar Biosciences’ SLIMamp chemistry, ONCO/Reveal custom panel design, and Pillar Variant Analysis Toolkit (PIVAT), which provide clinical laboratories with the means to offer their own customized, affordable, single-tube tests suitable for detecting clinically relevant mutations in formalin-fixed tissue or blood samples with a sensitivity of at least 1 per cent.
Date: February 19, 2019
Time: 8:00 a.m. PST / 11:00 a.m. EST
• Applications of SLIMamp, a single-vial NGS chemistry to rapidly profile tumour samples;
• Robust, sensitive mutation detection from samples with limited tumour input and liquid biopsies;
• Bioinformatic workflows using the Pillar Variant Analysis Toolkit for rapid mutation identification;
• Customization of the ONCO/Reveal assay to support clinical trials and identify emerging biomarkers.