Webinar - The Role of Pathology in Diagnosing Lysosomal Acid Lipase Deficiency (LAL-D) - Dr. Subrata Chakrabarti
Wed, 15 Feb 2017

chakrabartiLive Webinar Date/Time:
Wednesday, February 15, 2017, 12:30 – 13:30 ET

Dr. Subrata Chakrabarti
Chair, Department of Pathology and Laboratory Medicine at Western University and Chief of Pathology and Laboratory Medicine at London Health Sciences Centre & St. Joseph's Health Care, London, Ontario, Canada.

Lysosomal Acid Lipase Deficiency (LAL-D)
is an autosomal recessive lysosomal storage disorder [previously known as Wolman Disease (infants) and Cholesteryl Ester Storage Disease (children and adults)]. In pediatric and adult patients, nearly 50% progress to fibrosis, cirrhosis or liver transplant within 3 years of onset of symptoms.

Presentation Agenda:

  • Overview of Lysosomal Acid Lipase Deficiency (LAL-D)
  • Distinguishing LAL-D from other conditions
    • Differential diagnosis
    • Common histologic features
    • Evaluation of steatosis: microvesicular, macrovesicular, and mixed
  • Important role of the pathologist in suspicion of LAL-D

Educational Objectives:

At the end of this presentation the attendees will be able to:

  • Describe the epidemiological and clinical features of Lysosomal Acid Lipase Deficiency(LAL-D)
  • Describe the genetic abnormalities in LAL-D
  • Describe the pathogenesis of liver damage in LAL-D
  • Describe the histologic features of LAL-D
  • Describe the role of Pathologist in the management of LAL-D

Free Registration:
To register, please visit CLFLiverEducation.ca/lal-d.

Target audience: Healthcare professionals

Download the Poster PDF here.

We look forward to your participation. If you have any questions, please contact Karen Seto at kseto@liver.ca or 1-800-563-5483 ext. 4939.